SMA Research Platform

Evidence graph for Spinal Muscular Atrophy

Biology-first target discovery
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Christian Fischer / Bryzant Labs
15,934Targets
453Trials
84Drugs
7Datasets
7,947Sources
227,510Claims
263,546Evidence
58,010Hypotheses
← AF3 jobs·20260429_02804

03_NMJ_AGRN_LRP4_MuSK_ternary

iPTM
0.170
pTM
0.450
Ranking
0.330
Disorder
0.210
Clash
0
model 0·Loading…
Predicted Aligned ErrorLoading…
0 Å
30 Å
5 Model Seeds
ModeliPTMpTMRankingDisorderClash
model_0 ★ best0.1700.4500.3300.210
model_1 0.1700.4500.3300.200
model_2 0.1700.4500.3300.210
model_3 0.1100.4200.2800.210
model_4 0.1100.4200.2700.200
Input Sequences
#TypeLengthSequence
1protein169LDSGALHSEKALQSNHFELSLRTEATQGLVLWSGKATERADYVALAIVDGHLQLSYNLGSQPVVLRSTVPVNTNRWLRVV…
2protein207HIAKIERANLDGSERKVLINTDLGWPNGLTLDYDTRRIYWVDAHLDRIESADLNGKLRQVLVSHVSHPFALTQQDRWIYW…
3protein379TYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEY…
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