SMA Research Platform

Evidence graph for Spinal Muscular Atrophy

Biology-first target discovery
Christian Fischer / Bryzant Labs
15,934Targets
453Trials
84Drugs
7Datasets
7,947Sources
227,510Claims
263,546Evidence
58,010Hypotheses
← AF3 jobs·20260429_02804

09_SRSF1_HNRNPA1_SMN2_antagonism

iPTM
0.130
pTM
0.370
Ranking
0.280
Disorder
0.210
Clash
0
model 1·Loading…
Predicted Aligned ErrorLoading…
0 Å
30 Å
5 Model Seeds
ModeliPTMpTMRankingDisorderClash
model_0 0.1200.3900.2800.220
model_1 ★ best0.1300.3700.2800.210
model_2 0.1300.3400.2800.220
model_3 0.1200.3300.2700.220
model_4 0.1100.3100.2600.220
Input Sequences
#TypeLengthSequence
1protein248MSGGGVIRGPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVEFEDPRDAEDAVYGRDGYDYD…
2protein185MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVEEVDAAMNARPHKVD…
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