SMA Research Platform

Evidence graph for Spinal Muscular Atrophy

Biology-first target discovery
Christian Fischer / Bryzant Labs
15,934Targets
453Trials
84Drugs
7Datasets
7,947Sources
227,510Claims
263,546Evidence
58,010Hypotheses
← AF3 jobs·2026-04-25_batch_named

37_PAK4_LIMK2_kinase_X

iPTM
0.490
pTM
0.470
Ranking
0.640
Disorder
0.310
Clash
0
model 0·Loading…
Predicted Aligned ErrorLoading…
0 Å
30 Å
5 Model Seeds
ModeliPTMpTMRankingDisorderClash
model_0 ★ best0.4900.4700.6400.310
model_1 0.4900.4700.6300.280
model_2 0.4500.4500.6100.310
model_3 0.4600.4700.5700.230
model_4 0.4600.4500.5500.190
Input Sequences
#TypeLengthSequence
1protein142MNPAPGPRGPSAIPLSRKLLRIEGKSLRGHTCIGTKPVAAAYREPEKESSSSSQQNLCDEALKRLLEHIERVKDFDFKEG…
2protein203MSRLTLNKVIYRYEILKKIGAGSFGEAYLGLCSDGRQIAIKQIPIYSIQRVEIEALYGCAGGHPNIVRWFYSEKQGADLF…
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