SMA Research Platform

Evidence graph for Spinal Muscular Atrophy

Biology-first target discovery
Christian Fischer / Bryzant Labs
15,934Targets
453Trials
84Drugs
7Datasets
7,947Sources
227,510Claims
263,546Evidence
58,010Hypotheses
← AF3 jobs·batch_2026-05-05

AGRN_LG3_x_LRP4_B12

iPTM
0.240
pTM
0.690
Ranking
0.360
Disorder
0.050
Clash
0
model 0·Loading…
Predicted Aligned ErrorLoading…
0 Å
30 Å
5 Model Seeds
ModeliPTMpTMRankingDisorderClash
model_0 ★ best0.2400.6900.3600.050
model_1 0.2400.6900.3600.050
model_2 0.2100.6800.3300.040
model_3 0.1900.6700.3200.060
model_4 0.1700.6700.3000.050
Input Sequences
#TypeLengthSequence
1protein197GGFSGPHCEKGLVEKSAGDVDTLAFDGRTFVEYLNAVTESELANEIPVPETLDSGALHSEKALQSNHFELSLRTEATQGL…
2protein507RPRTGEENCNVNNGGCAQKCQMVRGAVQCTCHTGYRLTEDGHTCQDVNECAEEGYCSQGCTNSEGAFQCWCETGYELRPD…
Login → Command Center