SMA Research Platform

Evidence graph for Spinal Muscular Atrophy

Biology-first target discovery
Christian Fischer / Bryzant Labs
15,934Targets
453Trials
84Drugs
7Datasets
7,947Sources
227,510Claims
263,546Evidence
58,010Hypotheses
← AF3 jobs·20260514_afternoon_batch

ATF3_FULL_x_PAK1_KD_BIND

iPTM
0.150
pTM
0.280
Ranking
0.520
Disorder
0.700
Clash
0
model 0·Loading…
Predicted Aligned ErrorLoading…
0 Å
30 Å
5 Model Seeds
ModeliPTMpTMRankingDisorderClash
model_0 ★ best0.1500.2800.5200.700
model_1 0.1400.2800.4900.640
model_2 0.1200.2800.4600.620
model_3 0.0500.2500.4500.720
model_4 0.0800.2600.4500.670
Input Sequences
#TypeLengthSequence
1protein181MMLQHPGQVSASEVSASAIVPCLSPPGSLVFEDFANLTPFVKEELRFAIQNKHLCHRMSSALESVTVSDRPLGVSITKAE…
2protein76EISLPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKSEQKKNPQAVLDVLEFYNSKKTSNSQKYMSFTDKS
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