SMA Research Platform

Evidence graph for Spinal Muscular Atrophy

Biology-first target discovery
Christian Fischer / Bryzant Labs
15,934Targets
453Trials
84Drugs
7Datasets
7,947Sources
227,510Claims
263,546Evidence
58,010Hypotheses
← AF3 jobs·manual_2026-05-15_b

DEPTOR_PDZ_x_SMN1_PROL

iPTM
0.650
pTM
0.770
Ranking
0.810
Disorder
0.280
Clash
0
model 0·Loading…
Predicted Aligned ErrorLoading…
0 Å
30 Å
5 Model Seeds
ModeliPTMpTMRankingDisorderClash
model_0 ★ best0.6500.7700.8100.280
model_1 0.6100.7500.7800.280
model_2 0.6300.7600.7200.130
model_3 0.5000.7300.6900.280
model_4 0.4800.6900.5900.140
Input Sequences
#TypeLengthSequence
1protein88PGAPYARKTFTIVGDAVGWGFVVRGSKPCHIQAVDPSGPAAAAGMKVCQFVVSVNGLNVLHVDYRTVSNLILTGPRTIVM…
2protein35LGSMLISWYMSGYHTGYYMGFRQNQKEGRCSHSLN
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