SMA Research Platform

Evidence graph for Spinal Muscular Atrophy

Biology-first target discovery
Christian Fischer / Bryzant Labs
15,934Targets
453Trials
84Drugs
7Datasets
7,947Sources
227,510Claims
263,546Evidence
58,010Hypotheses
← AF3 jobs·2026-05-01_3004pt2

DOK7_full_x_LRP4_B12

iPTM
0.180
pTM
0.520
Ranking
0.400
Disorder
0.300
Clash
0
model 0·Loading…
Predicted Aligned ErrorLoading…
0 Å
30 Å
5 Model Seeds
ModeliPTMpTMRankingDisorderClash
model_0 ★ best0.1800.5200.4000.300
model_1 0.1800.5100.4000.300
model_2 0.1800.5100.3900.290
model_3 0.1700.5200.3800.290
model_4 0.1600.5100.3700.280
Input Sequences
#TypeLengthSequence
1protein504MTEAALVEGQVKLRDGKKWKSRWLVLRKPSPVADCLLMLVYKDKSERIKGLRERSSLTLEDICGLEPGLPYEGLVHTLAI…
2protein507RPRTGEENCNVNNGGCAQKCQMVRGAVQCTCHTGYRLTEDGHTCQDVNECAEEGYCSQGCTNSEGAFQCWCETGYELRPD…
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