SMA Research Platform

Evidence graph for Spinal Muscular Atrophy

Biology-first target discovery
Christian Fischer / Bryzant Labs
15,934Targets
453Trials
84Drugs
7Datasets
7,947Sources
227,510Claims
263,546Evidence
58,010Hypotheses
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GFRA3_LBD_x_ATF3_FULL

iPTM
0.140
pTM
0.360
Ranking
0.510
Disorder
0.660
Clash
0
model 0·Loading…
Predicted Aligned ErrorLoading…
0 Å
30 Å
5 Model Seeds
ModeliPTMpTMRankingDisorderClash
model_0 ★ best0.1400.3600.5100.660
model_1 0.1900.3600.4600.480
model_2 0.1800.3600.4600.490
model_3 0.1100.3500.4300.540
model_4 0.1200.3600.4200.510
Input Sequences
#TypeLengthSequence
1protein124DVSPYEDTVTSKPWKMNLSKLNMLKPDSDLCLKFAMLCTLNDKCDRLRKAYGEACSGPHCQRHVCLRQLLTFFEKAAEPH…
2protein181MMLQHPGQVSASEVSASAIVPCLSPPGSLVFEDFANLTPFVKEELRFAIQNKHLCHRMSSALESVTVSDRPLGVSITKAE…
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