SMA Research Platform

Evidence graph for Spinal Muscular Atrophy

Biology-first target discovery
Christian Fischer / Bryzant Labs
15,934Targets
453Trials
84Drugs
7Datasets
7,947Sources
227,510Claims
263,546Evidence
58,010Hypotheses
← AF3 jobs·manual_2026-05-15

LRP4_LDLRA_x_LIMK1_BIND

iPTM
0.250
pTM
0.300
Ranking
0.630
Disorder
0.740
Clash
0
model 0·Loading…
Predicted Aligned ErrorLoading…
0 Å
30 Å
5 Model Seeds
ModeliPTMpTMRankingDisorderClash
model_0 ★ best0.2500.3000.6300.740
model_1 0.2400.3000.6200.740
model_2 0.2200.3000.6000.730
model_3 0.2100.3000.6000.740
model_4 0.2000.2900.5900.740
Input Sequences
#TypeLengthSequence
1protein250PPAPRATGMSEKSPVLPNTPPTTLYSSTTRTRTSLEEVEGRCSERDARLGLCARSNDAVPAAPGEGLHISYAIGGLLSIL…
2protein116LVSIPASSHGKRGLSVSIDPPHGPPGCGTEHSHTVRVQGVDPGCMSPDVKNSIHVGDRILEINGTPIRNVPLDEIDLLIQ…
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