SMA Research Platform

Evidence graph for Spinal Muscular Atrophy

Biology-first target discovery
Christian Fischer / Bryzant Labs
15,934Targets
453Trials
84Drugs
7Datasets
7,947Sources
227,510Claims
263,546Evidence
58,010Hypotheses
← AF3 jobs·20260430_3004

MDM2_x_PTEN

iPTM
0.380
pTM
0.650
Ranking
0.500
Disorder
0.140
Clash
0
model 0·Loading…
Predicted Aligned ErrorLoading…
0 Å
30 Å
5 Model Seeds
ModeliPTMpTMRankingDisorderClash
model_0 ★ best0.3800.6500.5000.140
model_1 0.3300.6500.4400.100
model_2 0.3100.6500.4400.110
model_3 0.3000.6500.4300.120
model_4 0.2400.6600.3700.100
Input Sequences
#TypeLengthSequence
1protein85ETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIY…
2protein403MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAK…
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