SMA Research Platform

Evidence graph for Spinal Muscular Atrophy

Biology-first target discovery
Christian Fischer / Bryzant Labs
15,934Targets
453Trials
84Drugs
7Datasets
7,947Sources
227,510Claims
263,546Evidence
58,010Hypotheses
← AF3 jobs·batch_2026-05-05

mTOR_KIN_x_S6K1_KD

iPTM
0.220
pTM
0.440
Ranking
0.310
Disorder
0.100
Clash
0
model 0·Loading…
Predicted Aligned ErrorLoading…
0 Å
30 Å
5 Model Seeds
ModeliPTMpTMRankingDisorderClash
model_0 ★ best0.2200.4400.3100.100
model_1 0.1200.4400.2300.100
model_2 0.1000.4400.2200.100
model_3 0.1100.4400.2200.080
model_4 0.1100.4400.2200.090
Input Sequences
#TypeLengthSequence
1protein308LLKGHEDLRQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIE…
2protein322CFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLY…
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