SMA Research Platform

Evidence graph for Spinal Muscular Atrophy

Biology-first target discovery
Christian Fischer / Bryzant Labs
15,934Targets
453Trials
84Drugs
7Datasets
7,947Sources
227,510Claims
263,546Evidence
58,010Hypotheses
← AF3 jobs·2026-05-02_0105

NRG1_EGF_x_LIMK1_PDZ

iPTM
0.060
pTM
0.350
Ranking
0.380
Disorder
0.540
Clash
0
model 0·Loading…
Predicted Aligned ErrorLoading…
0 Å
30 Å
5 Model Seeds
ModeliPTMpTMRankingDisorderClash
model_0 ★ best0.0600.3500.3800.540
model_1 0.0500.3300.3700.510
model_2 0.0600.3600.2600.290
model_3 0.0500.3400.1900.150
model_4 0.0500.3400.1600.100
Input Sequences
#TypeLengthSequence
1protein70SHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGARCTENVPMKVQNQEKAEELYQKRVLTI
2protein53VTPVIEQILPDSPGSHLPHTVTLVSIPASSHGKRGLSVSIDPPHGPPGCGTEH
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