SMA Research Platform

Evidence graph for Spinal Muscular Atrophy

Biology-first target discovery
Christian Fischer / Bryzant Labs
15,934Targets
453Trials
84Drugs
7Datasets
7,947Sources
227,510Claims
263,546Evidence
58,010Hypotheses
← AF3 jobs·2026-05-02_0105

NRG1_EGF_x_PAK1_KD

iPTM
0.580
pTM
0.710
Ranking
0.630
Disorder
0.040
Clash
0
model 0·Loading…
Predicted Aligned ErrorLoading…
0 Å
30 Å
5 Model Seeds
ModeliPTMpTMRankingDisorderClash
model_0 ★ best0.5800.7100.6300.040
model_1 0.5500.7100.6000.040
model_2 0.5300.7000.5900.050
model_3 0.5100.7100.5900.080
model_4 0.5100.7000.5800.050
Input Sequences
#TypeLengthSequence
1protein70SHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGARCTENVPMKVQNQEKAEELYQKRVLTI
2protein252YTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAG…
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