SMA Research Platform

Evidence graph for Spinal Muscular Atrophy

Biology-first target discovery
Christian Fischer / Bryzant Labs
15,934Targets
453Trials
84Drugs
7Datasets
7,947Sources
227,510Claims
263,546Evidence
58,010Hypotheses
← AF3 jobs·20260514_morning_batch

NRG1_FULL_x_ERBB3_ECD

iPTM
0.810
pTM
0.530
Ranking
0.950
Disorder
0.390
Clash
0
model 1·Loading…
Predicted Aligned ErrorLoading…
0 Å
30 Å
5 Model Seeds
ModeliPTMpTMRankingDisorderClash
model_0 0.8000.5400.9500.400
model_1 ★ best0.8100.5300.9500.390
model_2 0.8000.5300.9400.400
model_3 0.8000.5400.9400.390
model_4 0.8000.5300.9400.390
Input Sequences
#TypeLengthSequence
1protein640MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRK…
2protein624GSEVGNSQAVCPGTLNGLSVTGDAENQYQTLYKLYERCEVVMGNLEIVLTGHNADLSFLQWIREVTGYVLVAMNEFSTLP…
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