SMA Research Platform

Evidence graph for Spinal Muscular Atrophy

Biology-first target discovery
Christian Fischer / Bryzant Labs
15,934Targets
453Trials
84Drugs
7Datasets
7,947Sources
227,510Claims
263,546Evidence
58,010Hypotheses
← AF3 jobs·20260514_afternoon_batch

NTRK2_ECD_x_SMN1_YGBOX

iPTM
0.330
pTM
0.620
Ranking
0.480
Disorder
0.190
Clash
0
model 0·Loading…
Predicted Aligned ErrorLoading…
0 Å
30 Å
5 Model Seeds
ModeliPTMpTMRankingDisorderClash
model_0 ★ best0.3300.6200.4800.190
model_1 0.3200.6200.4800.190
model_2 0.3300.6100.4800.180
model_3 0.3200.6200.4700.190
model_4 0.3100.6200.4600.190
Input Sequences
#TypeLengthSequence
1protein394CPTSCKCSASRIWCSDPSPGIVAFPRLEPNSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAF…
2protein43DSLDDADALGSMLISWYMSGYHTGYYMGFRQNQKEGRCSHSLN
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