SMA Research Platform

Evidence graph for Spinal Muscular Atrophy

Biology-first target discovery
Christian Fischer / Bryzant Labs
15,934Targets
453Trials
84Drugs
7Datasets
7,947Sources
227,510Claims
263,546Evidence
58,010Hypotheses
← AF3 jobs·20260514_afternoon_batch

RHEB_FULL_x_SMN1_PROL

iPTM
0.180
pTM
0.520
Ranking
0.350
Disorder
0.200
Clash
0
model 0·Loading…
Predicted Aligned ErrorLoading…
0 Å
30 Å
5 Model Seeds
ModeliPTMpTMRankingDisorderClash
model_0 ★ best0.1800.5200.3500.200
model_1 0.1700.5600.3500.210
model_2 0.1400.5300.3200.200
model_3 0.1600.5600.3000.120
model_4 0.0900.5300.2800.210
Input Sequences
#TypeLengthSequence
1protein184MPQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDING…
2protein35LGSMLISWYMSGYHTGYYMGFRQNQKEGRCSHSLN
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