SMA Research Platform

Evidence graph for Spinal Muscular Atrophy

Biology-first target discovery
Christian Fischer / Bryzant Labs
15,934Targets
453Trials
84Drugs
7Datasets
7,947Sources
227,510Claims
263,546Evidence
58,010Hypotheses
← AF3 jobs·2026-05-02_0105

TP53_DBD_x_MDM2_NTD

iPTM
0.160
pTM
0.620
Ranking
0.310
Disorder
0.110
Clash
0
model 1·Loading…
Predicted Aligned ErrorLoading…
0 Å
30 Å
5 Model Seeds
ModeliPTMpTMRankingDisorderClash
model_0 0.1500.6200.3100.130
model_1 ★ best0.1600.6200.3100.110
model_2 0.1600.6200.3100.110
model_3 0.1400.6200.2800.110
model_4 0.0900.6100.2500.110
Input Sequences
#TypeLengthSequence
1protein219SSSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKMFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVV…
2protein110MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSND…
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